News Archive
Northwestern’s Chemistry of Life Processes Institute Receives a Grant Award from The Michael J. Fox Foundation
As is the case with many other diseases, a protein is thought to be a key driver of Parkinson’s disease (PD). Thanks to a two-year $700,000 grant from The Michael J. Fox Foundation for Parkinson’s Research (MJFF), researchers in Northwestern’s Chemistry of Life...
Student Spotlight: Ananya Basu
Ananya Basu, a third-year PhD student, is using innovative approaches to overcome previously intractable targets in the Zhang Lab. Appointed to the CLP Predoctoral Training Program, she is being co-mentored by Zhang (chemistry) and Horvath (molecular biosciences)....
Transfer learning paves the way for new disease treatments
Technological advances in gene sequencing and computing have led to an explosion in the availability of bioinformatic data and processing power, respectively, creating a ripe nexus for artificial intelligence (AI) to design strategies for controlling cell behavior. In...
Neil Kelleher to Headline and Receive Distinguished Contribution Award at US HUPO 2024
Neil Kelleher, Walter and Mary Elizabeth Glass Professor of Chemistry, Molecular Biosciences, and Medicine at Northwestern University, will present his groundbreaking work and insights at US HUPO 2024 in Portland, Oregon next week as the 2024 recipient of the Donald...
At the Human Longevity Lab, Studying methods to slow or reverse aging
The Potocsnak Longevity Institute at Northwestern University Feinberg School of Medicine has launched the Human Longevity Laboratory, a longitudinal, cross-sectional study that will investigate the relationship between chronological age and biological age across...
CLP Seminar
Identifying Latent Functional Dynamics in Proteins Using Bio-NMR Jordan H Chill Associate Professor Bar Ilan University I lead the high-resolution biomolecular NMR research group at Bar Ilan University, Israel, following a post-doctoral fellowship at the NIH under...
Neuroscientist William Klein’s purpose and perseverance continues inspiring a new wave of efforts to combat Alzheimer’s disease
POSTED BY: WEINBERG COLLEGE OF ARTS & SCIENCES JANUARY 29, 2024 Battling Alzheimer’s disease has become William Klein’s life work – even if he never saw it coming. A progressive disease impacting memory, thinking, behavior, and other mental functions, Alzheimer’s...
Inside the chase after those elusive proteoforms
Human cells contain crowds of protein variants, but, especially in a time of funding challenges, chasing these proteoforms takes dogged persistence. Biology delivers a massive number of puzzles to proteoform hunters1,2. Proteoforms are the droves of protein variants...
When Instinct and Passion Collide
A longstanding member of Chemistry of Life Processes Institute’s Executive Advisory Board, Steven Deitcher, MD, Founder, CEO, and Chairman of Bespoke Biotherapeutics, has helped advance the Institute’s mission to conquer disease through protein-informed precision...
CLP Lambert Fellows Lean into Drug Discovery
For 13 years, the Chemistry of Life Processes Institute has provided financial support for promising undergraduate Chemistry majors to conduct research for two consecutive years through the Institute’s Lambert Fellowship Program. This year, three new fellows, Monica...
CLP Trainee IDP Workshop
Sheila Judge, PhD CLP Senior Director for Research, Education and Administration Sheila Judge will lead a hands-on, interactive workshop, using the MyIDP website offered by Science Careers to create an individual development plan. Trainees will take an online skills...
Pioneering Automated Proteoform Imaging of Ovarian Cancer Tissue
Investigators led by Neil Kelleher, PhD, professor of Medicine in the Division of Hematology and Oncology and of Biochemistry and Molecular Genetics, have developed an automated technique for imaging and identifying proteoforms in ovarian cancer tissue, according to...
CLP Welcomes Outstanding 2023-24 NIH Predoctoral Training Program Cohort
This fall, the Chemistry of Life Processes Institute welcomed a new cohort of Northwestern graduate students to its NIH Predoctoral Training Program. Alondra Sanchez, Ana Leal, Assa Magassa, Jun dos Remedios, Miguel Campos, and Yara Jabbour Al Maalouf joined...
CLP Summer Scholars Learn Research Fundamentals
Since its inception in 2009, the Chemistry of Life Processes Institute (CLP) has nurtured the research interests of dozens of undergraduates through its Summer Scholars Program. Program participants not only benefit from outstanding CLP faculty mentors; they receive...
Academic, Industry Leaders Gather for the 2023 International Top-Down Proteomics Symposium
One hundred and sixty world leaders in proteomics, proteoform biology, cell biology and genomics gathered October 3-5, 2023, at Northwestern’s Prentice Women’s Hospital to present their latest research findings and discuss next-generation proteomics at the second...
Richard Silverman Receives the 2024 Abeles and Jencks Award for the Chemistry of Biological Processes
Professor Richard B. Silverman of Northwestern University is the recipient of the 2024 Abeles and Jencks Award for the Chemistry of Biological Processes. His first publication with Dr. Abeles (“Inactivation of Pyridoxal Phosphate-Dependent Enzymes by Mono- and...
CLP Receives $2M to Prepare the Next Generation of Science Innovators
The Chemistry of Life Processes Institute (CLP) recently received a $2 million five-year National Institutes of Health (NIH) T32 training grant award (1 T32 GM 149439-01) to prepare a diverse cohort of students to lead the next wave of innovation and discovery at the...
New CLP summer research program trains and mentors NEIU undergraduates
This summer, Northwestern’s Chemistry of Life Processes Institute (CLP) welcomed the first participants of its Interdisciplinary Summer Undergraduate Research Experience (I-SURE), a new partnership with Northeastern Illinois University (NEIU). The eight-week summer...
Pioneering New Methods to Understand Protein Folding
Northwestern Medicine scientists have developed a new technique for measuring protein folding stability on an unprecedented scale, findings detailed in a new study published in Nature. While advances in technology have helped scientists discover new protein sequences...
New Leadership in the Department of Medicine
After 15 years of distinguished leadership in the Department of Medicine, Douglas E. Vaughan, MD, the Irving S. Cutter Professor of Medicine, has announced his intention to step down as chair of Medicine, effective September 1. Vaughan will be succeeded by Susan...
CLP undergraduate fellows bound for top graduate schools
Three outstanding graduating seniors, Rad Chrzanowski, Alejandro Medina, and Tiger Wang, will be heading to graduate school this fall after successfully completing the Chemistry of Life Processes Institute’s most rigorous undergraduate educational program, the Lambert...
Supercharged protein revs up biological processes
Utilizing advanced top-down proteomics approaches, Northwestern Proteomics researchers and collaborators in the Jewett Lab identified a proteoform responsible for increasing the speed of a well-known metabolic enzyme, Triosephosphate Isomerase (TPI) that drives energy...
CLP-Lurie Cancer Center Convergence Workshop: Cancer Genomics and Redox Epigenetics
CLP-Lurie Cancer Center Convergence Workshop: Cancer Genomics and Redox Epigenetics Join us for the CLP-Lurie Cancer Center Convergence Workshop on June 29, 2023, to learn about some of Northwestern’s most innovative cancer epigenetics research and methods and...
Silverman and Odom Elected to National Academy of Sciences
Richard B Silverman, PhD, professor of Chemistry in the Weinberg College of Arts and Sciences and of Pharmacology, along with two other Northwestern faculty members, have been elected to the National Academy of Sciences (NAS). Silverman, along with Timothy Earle, PhD,...
Northwestern student-athletes wrestle research
What do wrestling and research have in common? “Hard work and discipline,” says student-athlete Troy Fisher, one of four Northwestern wrestling team members who interned for the Kelleher Research Group last summer. Fisher and fellow students Jon Halvorsen, Andrew...
Former CLP trainee hunts for new therapies
In his current role as an early discovery scientist at Vividion Therapeutics (recently acquired by Bayer Pharmaceuticals) Northwestern alumnus Stefan Kathman, PhD (Chemistry ’16), draws from his interdisciplinary training as a participant in the Chemistry of Life...
Apply for an Undergraduate Research Grant!
Undergraduate Research Programs CLP encourages students who are interested in working on biomedical research problems across disciplinary boundaries to participate in the Institute’s undergraduate research programs. Students quickly become part of research teams and...
Life after Lyrica®
For most scientists, a major drug discovery happens rarely, if ever, in a lifetime. However, for Northwestern’s Richard (Rick) B. Silverman, the Patrick G. Ryan/Aon Professor, lightning struck in a big way with pregabalin, a compound he discovered in his lab....
Proteoform analysis uncovers new insights for drug developers
Two recent papers by Northwestern Proteomics researchers demonstrate the critical importance of proteoform analysis (the study of all of the different forms of proteins in the human body) in developing and refining treatments for cancer and other diseases....
Northwestern’s Neil Kelleher to receive Pittcon’s 2023 Pittsburgh Analytical Chemistry Award
The Society for Analytical Chemists of Pittsburgh (SACP) and the Pittsburgh Conference on Analytical Chemistry and Applied Spectroscopy (Pittcon), will present the Pittsburgh Analytical Chemistry Award to Northwestern’s Neil L. Kelleher, PhD, the Walter and Mary E....
International Top-Down Proteomics Symposium in Chicago, IL, October 3-5, 2023
Northwestern University’s Chemistry of Life Processes Institute will host the second International Top-Down Proteomics Symposium which will be held in Chicago, IL, October 3-5, 2023. The Symposium, a Consortium for Top-Down Proteomics event, will gather the global...
Calming the destructive cells of ALS by two independent approaches
Northwestern Medicine scientists have discovered two ways to preserve diseased upper motor neurons that would normally be destroyed in ALS, based on a study in mice. Upper motor neurons initiate movement, and they degenerate in ALS. These neurons have a...
First Transient Electronic Bandage Speeds Healing by 30 Percent
Northwestern Engineering researchers have developed a first-of-its-kind small, flexible, stretchable bandage that accelerates healing by delivering electrotherapy directly to the wound site. In an animal study, the new bandage healed diabetic ulcers 30 percent faster...
CLP Welcomes 2022-23 NIH Graduate Training Program Cohort
This year, Chemistry of Life Processes Institute welcomed five second-year predoctoral students (Ananya Basu, Minrui Luo, Daniel de Castro Assumpcao, Amy Tang and Anthony Pulvino) to its NIH-funded Graduate Training Program, now in its tenth year, and renewed...
Searching for clues to ovarian cancer biology
For over three years, Northwestern Proteomics has collaborated with the Women’s Health Integrated Research Center (WHIRC) and the Women’s Service Line at Inova Health System to better understand ovarian cancer in hopes of helping women receive the best treatment. The...
CLP Announces 2023 Cornew Innovation Award Recipients
Each year, the Chemistry of Life Processes Institute’s Executive Advisory Board selects a few exceptional high-risk, high-reward research projects to receive $50,000 to kickstart their research. The funding is part of the Institute’s Cornew Innovation Awards, a...
Robust and tunable performance of a cell-free biosensor encapsulated in lipid vesicles
In 2019, Chemistry of Life Processes Institute faculty members Neha Kamat and Julius Lucks received CLP Cornew Innovation Award funding to build an artificial cell biosensor. Science Avances recently published a paper about their work. Abstract Cell-free systems have...
Biological Sciences major Yulia Gutierrez receives CLP Undergraduate Research Award
Chemistry of Life Processes Institute recently named Northwestern junior Yulia Gutierrez the 2023 recipient of its CAURS Undergraduate Research Award. Gutierrez, a junior majoring in biological sciences and minoring in chemistry, is working in the laboratory of CLP...
Advancing organ transplantation outcomes
The Comprehensive Transplant Center (CTC) at Northwestern University’s Feinberg School of Medicine and the Northwestern Proteomics Center of Excellence (PCE) have teamed up to address issues and improve the safety and efficiency of organ transplants. Although the...
CLP-Feinberg Convergence Workshop targets unmet clinical needs
Fostering innovative research collaborations that address unmet clinical needs was the impetus behind a new team science workshop series launched by Northwestern’s Chemistry of Life Processes Institute (CLP). The inaugural CLP-Feinberg Convergence Workshop, held on...
Cornew Innovation Award collaborators examine the role of proteins in ALS
A team approach is essential when developing more effective treatments for ALS (amyotrophic lateral sclerosis), a progressive neurodegenerative disease affecting nerve cells in the brain and spinal cord. In her ongoing effort to determine the role of proteins in the...
CLP Core Expo 2022
Please join us on Tuesday, November 10, 2022, 11:00 - 1:00 p.m., for the 2022 CLP Core Expo. The Core Expo gives Feinberg physician-scientists and their labs the opportunity to learn about the instrumentation and services provided by CLP core facilities. Consult in...
Conquering the Human Proteome
Neil Kelleher has previously discussed the many merits of top-down proteomics and how they will enable “the earlier and more precise detection of all human disease.” He is currently the Walter and Mary Elizabeth Glass Professor of Molecular Biosciences, Professor of...
Tong Zhang, PhD, wins Nikon Small World 2022 Photomicrography Competition | Image of Distinction Award
Nikon Small World 2022 Photomicrography Competition Image of Distinction 2022 Photomicrography Competition A double nuclei Bovine Pulmonary Artery Endothelial (BPAE) cell Dr. Tong Zhang Affiliation Northwestern University Biological Imaging Facility Evanston,...
Northwestern to lead a new national Center for Chemical Innovation
Northwestern University has been chosen by the National Science Foundation to lead a new Center for Chemical Innovation (CCI). The national center’s diverse research team will focus on harnessing the power of biocatalysis found in nature to forge new processes for a...
Chemistry of Life Processes Institute Financial Coordinator Position
Financial Coordinator Position, Job ID 45974 Chemistry of Life Processes Institute, Northwestern University The Chemistry of Life Processes Institute (CLP) at Northwestern University invites applications for the position of Financial Coordinator. The Financial...
Move over, DNA. The future is protein.
In the coming decades, efforts to understand disease will be propelled by building 3D maps of protein arrangements in cells over time, a team of scientists says. A workshop about the study of proteins on a large scale — proteomics — yielded a perspective piece that is...
New Technique Improves Proteoform Imaging in Human Tissue
Investigators led by Neil Kelleher, PhD, professor of Medicine in the Division of Hematology and Oncology and of Biochemistry and Molecular Genetics, have developed a new imaging technique that increases the detection of intact proteoforms by fourfold when compared to...
An unconventional approach to drug discovery
“While scientists have made great strides in understanding the human genome, our understanding of human genetics hasn’t been effectively translated into new therapeutics,” says Xiaoyu Zhang, Assistant Professor of Chemistry at Northwestern and member of the Chemistry...
After the Genome—A Brief History of Proteomics
With researchers touting recent success in sequencing the human genome’s remaining gaps, an emerging frontier is proteomics: identifying and studying an entire set of expressed proteins in the human body and other organisms. Collectively, these sets are called...
Diving deeper into the proteome
As new technology enables researchers to find and characterize less-common post-translational modifications that drive gene expression and cellular metabolism, the movement to catalog the entire human proteome gains momentum Sequencing the human genome provided...
Undergraduate researchers shine at annual CLP Summer Symposium
The art of communicating complex science is a learned skill for most young researchers. This summer, eight undergraduate CLP Lambert Fellows and Summer Scholars were given the opportunity to practice their scientific presentation skills at Chemistry of Life Processes...
2022 Lambert Fellows aim to push the frontiers of chemistry
Two Northwestern chemistry majors, JoJo Holm and Anthony Tam, have joined the ranks of a select group of students who have received Lambert Fellowships, Chemistry of Life Processes Institute’s most prestigious undergraduate award. Each student will receive multi-year...
Congresswoman Jan Schakowsky visits Northwestern Proteomics
Chemistry of Life Processes Institute (CLP) director Neil L. Kelleher and members of the CLP and Northwestern Proteomics team welcomed U.S. Congresswoman Jan Schakowsky from the 9th District of Illinois to Silverman Hall today to discuss the promise and potential of...
2022 CLP Summer Scholars savor the rewards of research
Three Northwestern undergraduates, Izzy He, Connor Moore, and Sean Pascoe, were recipients of the 2022 Chemistry of Life Processes Institute (CLP) Summer Scholars Research Program Award. Each will receive $4,500 to spend the summer quarter working with a CLP faculty...
Students, staff, and investigators have fun and learn about research tools at the 2022 CLP Core Crawl
As merengue music echoed from the ice cream truck parked underneath the bridge connecting the east and west sides of Silverman Hall, visitors streamed into the twelfth annual CLP Core Crawl. Hot pizza, beer and frozen treats awaited nearly 200 Northwestern...
Biotech leader transcends boundaries
Ever since her days as a graduate student in Northwestern’s Interdepartmental Neuroscience (NUIN) graduate program, Mani Mohindru, PhD, chief executive officer of Novasenta, has defied boundaries. She chose NUIN for its interdepartmental approach that gives students...
Chemistry of Life Processes Institute Financial Assistant Position
Financial Assistant Position Chemistry of Life Processes Institute, Northwestern University The Chemistry of Life Processes Institute (CLP) at Northwestern University invites applications for the position of Financial Assistant. The Financial Assistant is responsible...
ChemCore-Medicinal Chemistry Project Manager Position
July 12, 2022 ChemCore-Medicinal Chemistry Project Manager Chemistry of Life Processes Institute, Northwestern University The Chemistry of Life Processes Institute (CLP) at Northwestern University invites applications for the position of ChemCore Project Manager. This...
New Views of Old Proteins: Clarifying the Enigmatic Proteome
The National Institutes of Health Office of Strategic Coordination convened a virtual meeting to foster discussion among experts on existing gaps and opportunities within the functional proteomics field. Organized by the National Institutes of Health Office of...
Unlocking the Human Proteome
Neil Kelleher, PhD, has been weighing proteins since 1999, when, as a young professor, he opened his independent laboratory at the University of Illinois in Urbana-Champaign. His goal then, he says, was the same as his goal now: “to weigh every human protein.” More...
Pushing the boundaries of proteomics technology
Setting audacious goals for technology innovation is a critical component of the Human Proteoform Project, a $1.3 billion movement to weigh and characterize every protein variation, (called proteoforms) in the human body. A new technology announced today,...
CLP/Oppenheimer to Host 4th Annual Investor Summit
Biopharma investors, innovators, and industry executives will get an exclusive look at next-generation protein therapeutics developed by Northwestern’s top translational scientists at the fourth annual Biotech by the Lake Investor Summit on June 28, 2022, 9:00 a.m. –...
This time around, Lyrica’s inventor is developing his Northwestern discoveries at his own biotech
Richard Silverman was left in the dark for the last five years of clinical development of the drug he discovered. The Northwestern University professor found out about the first approval of Lyrica, in the last few days of 2004, like most other people: in the...
Potential ALS treatment may repair axons of diseased neurons
New research on the experimental drug, NU-9, invented and developed by two Northwestern University scientists to treat ALS (amyotrophic lateral sclerosis), shows it is more effective than existing FDA-approved drugs for the disease. More importantly, NU-9 has an...
Upcyling polyester could reduce plastic waste
Less than 10% of the 380 million metrics tons of annually produced plastics are currently recycled in the U.S., creating a global environmental threat caused by plastic production and the absorption of millions of tons of waste into bodies of water each year. When you...
Top-Down Proteomics Reveals the KRAS Proteoform Landscape in Colorectal Cancer
Proteomics is a broad term that can generically be defined as the study of the proteome, or the landscape of proteins expressed within a given biological context. More specifically, proteomics can entail investigating aspects of the proteome such as protein expression...
Three Promising Undergraduates Receive CLP Lambert Fellowships
Northwestern Chemistry students, Rad Chrzanowski, Alejandro Medina, and Tiger Wang, were the recipients of this year’s Lambert Fellowship, the most prestigious undergraduate award awarded by Chemistry of Life Processes Institute. Recipients were selected based on...
The Giving Back Principle
Growing up in Germany as a young person with allergies, Ulrich Thienel, MD, PhD, Chief Executive Officer of ReAlta Life Sciences and member of Chemistry of Life Processes Institute’s (CLP) Executive Advisory Board, spent a lot of time in the doctor’s office. That...
Tumors dramatically shrink with new approach to cell therapy
Northwestern University researchers have developed a new tool to harness immune cells from tumors to fight cancer rapidly and effectively. Their findings, published January 27 in the journal Nature Biomedical Engineering, showed a dramatic shrinkage in tumors in mice...
Researchers identify proteins that could predict liver transplant rejection
Northwestern University scientist have discovered families of proteins in the body that could potentially predict which patients may reject a new organ transplant, helping inform decisions about care. The advancement marks the beginning of a new era for more precise...
Guillermo Ameer Awarded the Technology Innovation and Development Award
Chemistry of Life Processes Institute member Guillermo A. Ameer, Daniel Hale Williams Professor of Biomedical Engineering at the McCormick School of Engineering and Surgery at the Feinberg School of Medicine, has been given the the 2022 Technology Innovation and...
CLP announces Undergraduate Research Awardees
Two outstanding Northwestern undergraduates, Hasan Munshi and Lauren Hyoseo Yoon, were named this year’s recipients of the Chemistry of Life Processes Institute (CLP) \Undergraduate Research Award. Each will receive a stipend as well as the opportunity to present...
Human Proteoform Project Could Be Biology’s Next Moonshot
Eight years ago, an international team of researchers proposed that the term “proteoform” be adopted to describe the vast number of forms of protein products from our genes—including changes due to genetic variations, alternative RNA splicing, and post-translational...
Researchers pinpoint how Zika virus evades cell’s antiviral response
The world knows SARS-CoV-2 intimately now, but there are more than 200 virus species capable of infecting humans and causing disease. And they all want to do the same thing: invade the host cells, hijack each cell’s machinery and reproduce. The human immune response...
Nanotherapy offers new hope for the treatment of Type 1 diabetes
Individuals living with Type 1 diabetes must carefully follow prescribed insulin regimens every day, receiving injections of the hormone via syringe, insulin pump or some other device. And without viable long-term treatments, this course of treatment is a lifelong...
CLP announces 2021-22 Cornew Innovation Awardees
Chemistry of Life Processes Institute has selected two high-risk, potentially high-reward biomedical research projects to receive CLP Cornew Innovation Awards. The 2021-22 awards will support the development of new technology for creation of viral nanoparticles for...
ALS therapy should target brain, not just spine
The brain is indeed a target for treating ALS (amyotrophic lateral sclerosis), Northwestern Medicine scientists have discovered. This flips a long-standing belief that the disease starts in the spinal motor neurons and any therapy would need to target the spine as the...
Community drives CLP training program alum
Meet Luis Schachner, Post Doctoral Fellow at Genentech. CLP Predoctoral Training Program alum and graduate of Northwestern’s Chemistry Program. His CLP Training Program Preceptors were Neil Kelleher and Yuan He. Luis also served as CLP's inaugural...
Pharma pulls CLP training program alum
Meet Henrique dos Santos Seckler, PhD, Scientist 1 at Alliance Pharma. Henrique is a CLP Predoctoral Training Program alum and a graduate of Northwestern’s Chemistry Program. His CLP Training Program preceptors were Neil Kelleher, John Wilkins, and Shad Thaxton. What...
Human Proteoform Project to map proteins in human body
Now that the Human Genome Project has officially wrapped, an international team of researchers will map the entire collection of proteins in the human body. Plans and goals for the Human Proteoform Project were outlined in a paper published last week (Nov. 12) in the...
CLP training program alum mixes science with business
Meet Emma Coughlin, PhD, head of bioengineering at biotechnology startup Minutia. Emma is a CLP Predoctoral Training Program alum and graduate of Northwestern’s Interdisciplinary Biological Sciences Program. Her CLP Training Program Preceptors were Thomas Meade and...
CLP champion Stuart Cornew thinks big
“I’m the luckiest human you’ve ever met,” says Stuart Cornew, founder of Chemistry of Life Processes Institute’s (CLP) Executive Advisory Board (EAB) and one of the Institute’s earliest champions. “I was diagnosed with a dread disease [multiple myeloma, a type of...
PhD Finds Her Calling in Professional Development
Meet Elamar Hakim Moully, PhD, program development specialist of myCHOICE at the University of Chicago. Elamar is a CLP Predoctoral Training Program alum, and graduate of Northwestern’s Chemistry Program. Her CLP Training Program Preceptors were Milan Mrksich and Chad...
From Scientist to Science Writer
Meet Allessandra DiCorato, PhD, science writer at The Broad Institute of MIT and Harvard. Allessandra is an alum of the Chemistry of Life Processes Institute Predoctoral Training Program and graduate of Northwestern’s Material Science and Engineering program. Her CLP...
Northwestern-invented biomaterial technology moves from lab bench to the orthopaedic market
Northwestern biomedical engineer Guillermo A. Ameer has achieved a rare, major accomplishment. A medical product based on novel biomaterials pioneered in his laboratory will be widely available for use in musculoskeletal surgeries to directly benefit patients. The...
‘Single-cell proteomics takes centre stage’ Nature 9/20/21
Claudia Ctortecka was both sceptical and intrigued when her thesis adviser told her in 2018 about a new method that uses mass spectrometry to analyse the protein contents of individual cells. When he said he was looking for someone to pursue this single-cell...
Neil Kelleher Appointed Director of Chemistry of Life Processes Institute
Renowned proteomics expert Neil L. Kelleher has been named director of the Chemistry of Life Processes Institute (CLP), effective Sept. 1. Kelleher succeeds Thomas O’Halloran, who led CLP since it launched in 2005. Kelleher is the Walter and Mary Glass Professor of...
CLP Lambert Fellow Spotlight: Ellen Chao
Ellen Chao was awarded the Chemistry of Life Processes Institute (CLP) Lambert Fellowship in 2019 and 2020. The Lambert Fellowship is CLP’s most prestigious undergraduate award. It is designed to provide multi-year funding for hands-on laboratory research for rising...
New technique identifies proteins in the living brain
For the first time, researchers have developed a successful approach for identifying proteins inside different types of neurons in the brain of a living animal. Led by Northwestern University and the University of Pittsburgh, the new study offers a giant step toward...
Investors, Biotech Leaders and Neuroscience Experts Convene for ‘Biotech by the Lake 2021’
More than 250 biotech investors, industry members and investigators gathered online on June 22, 2021 for the third-annual Biotech by the Lake Investor Summit hosted by Northwestern University’s Chemistry of Life Processes Institute (CLP), Oppenheimer & Co., and...
Uniquely Coronavirus
Research about a potential drug target for the coronavirus will be the focus of Northwestern's High Throughput Analysis Core's (NU-HTA) first User Spotlight Seminar on Tuesday, July 27, at 12:00 p.m. at the Feinberg School of Medicine. HTAL user Monica Rosas Lemus,...
A biological fireworks show, 300 million years in the making
Five years ago, researchers at Northwestern University made international headlines when they discovered that human eggs, when fertilized by sperm, release billions of zinc ions, dubbed “zinc sparks.” Now, Northwestern has teamed up with the U.S. Department of...
Case Studies of Proteoforms in Human Health and Disease
WHEN: Tuesday, June 29, 2021, 11 AM - 12 PM (ONLINE) WHAT: Neil L. Kelleher, PhD, Walter and Mary Glass Professor of Molecular Biosciences, Professor of Chemistry; Faculty Director of Northwestern Proteomics; and Interim Director of Chemistry of Life Processes...
Rare mineral from rocks found in mollusk teeth
Northwestern University researchers have, for the first time, discovered a rare mineral hidden inside the teeth of a chiton, a large mollusk found along rocky coastlines. Before this strange surprise, the iron mineral, called santabarbaraite, only had been documented...
New Method to Analyze Nucleosomes
Northwestern Medicine scientists have developed a new method to analyze the protein composition of intact nucleosomes without losing combinatorial information present in chromatin. The technique, called Nuc-MS, could help scientists more efficiently uncover the...
Reimagining Science Through ‘Art Spectra’
Sitting in ‘easy pose’ at a Midwestern art and meditation festival last year, Chemistry of Life Processes Institute (CLP) predoctoral trainee Luis Schachner began an unexpected journey that led to the discovery of his inner artist and a new role as CLP’s first...
Leading Scientific Societies Recognize Northwestern Biochemist’s Seminal Contributions
Northwestern University’s Amy C. Rosenzweig, the Weinberg Family Distinguished Professor of Life Sciences and Professor of Molecular Biosciences and Chemistry, received two prestigious scientific awards in 2021 for her work at the forefront of biochemistry. She...
Implanted wireless device triggers mice to form instant bond
Northwestern University researchers are building social bonds with beams of light. For the first time ever, Northwestern engineers and neurobiologists have wirelessly programmed — and then deprogrammed — mice to socially interact with one another in real time. The...
Biotech by the Lake Annual Investor Conference to Convene on June 22
Biotech investors, industry members and academic innovators are invited to attend ‘Biotech by Lake 2021 Investor Summit’, hosted by Chemistry of Life Processes Institute (CLP) at Northwestern. The third annual program will highlight next-generation therapies and...
CLP Member Thomas J. Meade, PhD, Honored with University Teaching Award
Chemistry of Life Processes Institute member Thomas J. Meade, PhD, is one of five faculty members being honored with the 2021 University Teaching Awards. The annual honor is given to professors who demonstrate excellence and innovation in undergraduate education. The...
Understanding how DNA repairs itself may lead to better cancer treatments
From cancer treatment to sunlight, radiation and toxins can severely damage DNA in both harmful and healthy cells. While the body has evolved to efficiently treat and restore damaged cells, the mechanisms that allow this natural repair remain misunderstood. In a new...