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TITLE: A Beginners’ Guide to Academic Drug Development at NU

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PRESENTER:  William (Bill) Sargent, PhD

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WHEN:  Wednesday, January 27, 12:00 PM

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WHERE:  ZOOM 

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William (Bill) Sargent, PhD, former President of Lorex Pharmaceuticals and current member of Chicago Innovation Mentors, has over 30 years in the pharmaceutical industry, preceded by 10 years as an independent researcher in academia. As CLP’s entrepreneur-in-residence, he will provide mentoring in the drug development process, from initiation to FDA marketing approval, to interested researchers across campus looking to explore commercialization.

Sargent is well-versed in the therapeutic development emerging from local universities, having served as member of the Chicago Innovation Mentors (CIM) program since 2013. Previously, he held senior positions at Pfizer, Hoechst-Roussell Pharmaceuticals, Lorex Pharmaceuticals, Searle, and Pharmacia. As President and General Manager of Lorex, he oversaw FDA approval for direct to consumer advertising for the lead product Ambien. He led the international launch of Sutent® for renal cell carcinoma and gastrointestinal stromal cancer while Senior Medical Director and Team Leader for the anti-angiogenic portfolio at Pfizer. Dr. Sargent received a PhD in physiology from the University of Tennessee Center for the Health Sciences where he remained as faculty in Physiology and Biophysics for approximately 10 years.

As Entrepreneur-in-Residence in CDT, Sargent will be available for consultation to faculty, students and staff interested in developing potential therapies emerging from their translational research. Central to this process will be his assistance in the creation of a Target Product Profile (TPP) for compounds under development. The Profile will enable the entrepreneur to start therapeutic development process with the end in mind. “The TPP is most helpful early on in development, as it sets the road map for achieving the IND and provides a long-term view of what data will be needed to validate claims in the final package insert,” said Sargent. “It’s also a great tool to form the basis of a value proposition and for later interaction with the FDA.”

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