NU-HTA USER SPOTLIGHT SEMINAR: hiPSC Models of Sudden Cardiac Death
When: Wednesday, June 15, 2022, 12 – 1PM CST
Where: Online
Who: Malorie Blancard, PhD, Postdoctoral Fellow, Department of Pharmacology, Feinberg School of Medicine, Northwestern
We are modeling sudden cardiac death risk prediction using patient-specific human iPSC-derived cardiomyocytes (hiPSC-CMs). Sixty individuals have been recruited and classified ranging from healthy controls with no known cardiac disease to individuals that show the highest SCD risk. Contractility and electrophysiological properties of hiPSC-CMs were measured using high-throughput systems such as ‘Flexcyte 96’ (Nanion).
The High Throughput Analysis Core (NU-HTA) is a shared, open-access resource within the Chemistry of Life Processes Institute that provides equipment and expertise for the development and execution of high throughput biological analysis and screening. The facility is fully equipped with state-of-the-art liquid handling and microplate detection instrumentation.